Staff Software Engineer
DavidJoseph&- Location
- San Francisco, United States
- Workplace
- Hybrid
- Employment
- Full Time
- Salary
- USD 210–260/wk
Posted 4d ago
Staff Software Engineer
Our client is a seed-stage healthcare/life-sciences company building AI agents that automate clinical trial workflows — attacking one of the biggest bottlenecks in drug development. Backed by $7M+ in funding, the platform is already used across 400+ research sites. This is a founding tech-lead role on a small, high-impact engineering team.
The role
A hands-on Staff Software Engineer (8+ yrs) to be the technical anchor of a small team — writing and reviewing code daily while mentoring three junior engineers and establishing engineering best practices, and partnering with product, customer success, and founders to ship zero-to-one AI-powered products.
Responsibilities
- Own and build AI-powered products end-to-end (agentic workflows, LLM features with production evals)
- Technical lead and mentor for three junior engineers; set best practices for code review and process
- Partner with CTO, PM, and customer success to shape zero-to-one products
- Architect and deliver full-stack apps across frontend, backend, infra, and data pipelines
Must-have
- Tech lead / technical anchor experience on an engineering team
- Full-stack product engineer who owns features end-to-end (backend-leaning generalists welcome)
- Mentor / bar-raiser able to establish engineering best practices
- 8–15 yrs full-stack product engineering, building AI/LLM features
- Zero-to-one, customer-facing product background (not deep infra)
- Recent (1–2 yrs) hands-on shipping of LLM features / AI agents in production
Nice-to-have
- Mix of startup (seed–Series B, founding/early hire) and larger-company experience
- CS degree or equivalent
- Production AI evals / LLM observability (LangSmith, Braintrust, W&B); multi-step agentic pipelines
- Genuine interest in bio, life sciences, or healthcare
Compensation & logistics
Base salary
$210K–$260K, flexible for exceptional candidates
Equity
1–1.5%
Full-time, hybrid
3 days/week in-office (Mon, Tue, Thu), Financial District, San Francisco
Visa
open to transfers (e.g., OPT, H-1B transfers); no new sponsorships
Interview process
3 steps — 30-min intro call, virtual system design interview, final on-site (technical + behavioral + team lunch)
Skills
- LLM
- LangSmith
More jobs at DavidJoseph&
All 36Senior Software Engineer
DavidJoseph& · New York · United States · USD 230–280/wk · yesterday
Senior Full-Stack Software Engineer
DavidJoseph& · San Francisco, United States · USD 180–280/hr · yesterday
Software Engineer
DavidJoseph& · New York · United States · yesterday
Software Engineer
DavidJoseph& · San Francisco, United States · USD 140–285/wk · 2d ago
Member of Technical Staff, Compiler
DavidJoseph& · New York · United States · USD 150–300/hr · 2d ago
Similar roles
Principal Software Architect
Abacus Insights · United States · today
Principal Software Engineer
Lambda · Bellevue Office · today
Founding Flight Software Engineer
Fortastra · Torrance, CA · USD 180,000–250,000/yr · today
Senior Software Engineer – Full Stack
Empower Pharmacy · US · today
Senior Computer Vision Engineer, Space
Anduril Industries · Costa Mesa, California, United States · USD 191,000–253,000/yr · today
Senior Computer Vision Engineer, Space
Anduril Industries · Washington · District of Columbia · United States · USD 191,000–253,000/yr · today